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Xinliang Mao Selected Research

Bortezomib (Velcade)

1/2013Dissecting bortezomib: development, application, adverse effects and future direction.
1/2011The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discovery.
4/2009Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-kappaB with antimyeloma activity in vitro and in vivo.
7/2008TROSY-based NMR evidence for a novel class of 20S proteasome inhibitors.

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Xinliang Mao Research Topics

Disease

53Neoplasms (Cancer)
12/2021 - 11/2003
29Multiple Myeloma
01/2022 - 12/2007
16Leukemia
08/2017 - 08/2008
9Hematologic Neoplasms (Hematological Malignancy)
11/2017 - 08/2008
7Carcinogenesis
10/2021 - 03/2014
4Chronic Disease (Chronic Diseases)
12/2021 - 09/2018
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2021 - 11/2012
4Prostatic Neoplasms (Prostate Cancer)
01/2019 - 01/2011
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 07/2014
3Lung Neoplasms (Lung Cancer)
11/2012 - 11/2003
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021 - 11/2012
2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell)
01/2019 - 04/2016
2Breast Neoplasms (Breast Cancer)
03/2017 - 10/2014
2Lymphoma (Lymphomas)
08/2015 - 01/2011
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2015 - 07/2014
2Body Weight (Weight, Body)
01/2014 - 11/2013
1Genetic Translocation (Chromosomal Translocation)
01/2022
1Communicable Diseases (Infectious Diseases)
12/2021
1Parkinson Disease (Parkinson's Disease)
10/2021
1Huntington Disease (Huntington's Disease)
01/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021
1Cardiovascular Diseases (Cardiovascular Disease)
11/2020
1Arthritis (Polyarthritis)
11/2020
1Asthma (Bronchial Asthma)
11/2020
1Nervous System Diseases (Neurological Disorders)
11/2020
1Type 2 Diabetes Mellitus (MODY)
01/2020
1Noncommunicable Diseases
01/2020
1Acquired Immunodeficiency Syndrome (AIDS)
02/2019
1Medulloblastoma
11/2018
1Basal Cell Carcinoma (Rodent Ulcer)
11/2018
1Inflammation (Inflammations)
09/2018
1Anemia
01/2018

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
10/2021 - 05/2008
11Pharmaceutical PreparationsIBA
01/2021 - 08/2008
7Transcription Factors (Transcription Factor)IBA
01/2022 - 03/2016
6UbiquitinIBA
02/2019 - 09/2008
68- ethoxy- 2- (4- fluorophenyl)- 3- nitro- 2H- chromeneIBA
08/2017 - 02/2011
5Cyclin D2IBA
04/2011 - 12/2007
4Deubiquitinating EnzymesIBA
10/2021 - 01/2017
4EnzymesIBA
01/2020 - 03/2010
4Proteasome Endopeptidase Complex (Proteasome)IBA
02/2019 - 11/2008
4Ligases (Synthetase)IBA
02/2019 - 03/2016
4Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019 - 04/2016
4Clioquinol (Vioform)FDA Link
07/2014 - 11/2008
4Bortezomib (Velcade)FDA Link
01/2013 - 07/2008
3TOR Serine-Threonine KinasesIBA
01/2021 - 01/2014
36-bromo-8-ethoxy-3-nitro-2H-chromeneIBA
08/2014 - 06/2013
3Proteasome InhibitorsIBA
01/2013 - 07/2010
2Cyclin D1IBA
10/2021 - 05/2008
2SaponinsIBA
11/2020 - 01/2018
2ErbB Receptors (EGF Receptor)IBA
05/2020 - 01/2017
2PIK-C98IBA
12/2019 - 01/2015
2Oncogene Proteins (Oncogene Protein)IBA
02/2019 - 01/2018
2Annexin A5IBA
11/2018 - 07/2010
2Caspase 3 (Caspase-3)IBA
11/2018 - 09/2013
2Peptides (Polypeptides)IBA
11/2017 - 06/2016
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
08/2015 - 06/2014
2Phosphatidylinositols (Phosphatidylinositol)IBA
03/2014 - 02/2011
2Cyproheptadine (Periactin)FDA Link
12/2013 - 08/2008
2TriterpenesIBA
11/2013 - 04/2009
2Amitriptyline (Elavil)FDA LinkGeneric
09/2013 - 04/2011
2CyclinsIBA
02/2011 - 08/2008
2LigandsIBA
01/2010 - 11/2008
2Death Domain ReceptorsIBA
01/2010 - 11/2008
2Cyclin DIBA
04/2009 - 05/2008
1CurcuminIBA
12/2021
1DiarylheptanoidsIBA
12/2021
1Glucose (Dextrose)FDA LinkGeneric
10/2021
1Huntingtin ProteinIBA
01/2021
1TensinsIBA
01/2021
1Glutamine (L-Glutamine)FDA Link
01/2021
1NucleotidesIBA
01/2021
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021
1Protein Kinases (Protein Kinase)IBA
01/2021
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
01/2021
1DiosgeninIBA
11/2020
1PhytochemicalsIBA
11/2020
1Synthetic DrugsIBA
11/2020
1ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA
01/2020
1GlucosidasesIBA
01/2020
1Cyclin EIBA
02/2019
1Cisplatin (Platino)FDA LinkGeneric
01/2019
1CaspasesIBA
12/2018
1Matrix Metalloproteinases (MMPs)IBA
12/2018
1CalciumIBA
12/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2018
1HhAntag691IBA
11/2018
1LipidsIBA
09/2018
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2018
1eltrombopagFDA Link
01/2018
1Thrombopoietin ReceptorsIBA
01/2018
1Prostaglandins FIBA
01/2018
1Thioctic Acid (Lipoic Acid)IBA
11/2017
1Hyaluronic Acid (Hyaluronan)IBA
11/2017
1PapainIBA
11/2017

Therapy/Procedure

12Therapeutics
12/2021 - 09/2006
7Oral Administration
01/2018 - 09/2013
3Drug Therapy (Chemotherapy)
11/2017 - 09/2006
2Hematopoietic Stem Cell Transplantation
10/2017 - 07/2014
1Long-Term Care
01/2020